Judge D M, McGlynn T J, Abt A B, Luderer J R, Ward S P
Arch Pathol Lab Med. 1977 Jul;101(7):362-5.
The histopathologic characteristics of a patient with progressive myopathy, renal failure, hemoptysis, and a fulminant terminal event demonstrated a diffuse vasculitis, type 2 fiber atrophy of muscle, and linear IgG staining of the basement membranes of skeletal muscle fibers and of glomerular capillary basement membranes. Interpretation of electron micrographs confirmed that there was thickening of muscle basement membranes. The data suggest the presence of an antibody to a basement membrane antigen shared by muscle and kidney.
一名患有进行性肌病、肾衰竭、咯血并经历暴发性终末事件的患者，其组织病理学特征显示为弥漫性血管炎、肌肉Ⅱ型纤维萎缩，以及骨骼肌纤维和肾小球毛细血管基底膜的基底膜呈线性IgG染色。电子显微镜照片的解读证实肌肉基底膜增厚。这些数据表明存在一种针对肌肉和肾脏共有的基底膜抗原的抗体。
