大鼠注射震颤素或氧化震颤素后震颤与脑乙酰胆碱浓度变化之间的关系。
The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat.
作者信息
Cox B, Potkonjak D
出版信息
Br J Pharmacol. 1969 Feb;35(2):295-303.
Abstract
- The relationship between tremor and change in brain acetylcholine concentration after the injection of tremorine or oxotremorine has been investigated in rats.2. Tremorine produced a significant increase in whole brain acetylcholine and in tremor 5 min after injection. After this time tremor subsided but brain acetylcholine continued to increase.3. Oxotremorine produced tremor within 30 sec. This became maximal within 5 min of injection and then declined rapidly. The brain acetylcholine concentration showed a significant increase 5 min after injection and continued to increase until 30 min afterwards.
摘要
已经在大鼠中研究了注射震颤素或氧化震颤素后震颤与脑乙酰胆碱浓度变化之间的关系。
注射震颤素后5分钟，全脑乙酰胆碱和震颤显著增加。此后震颤消退，但脑乙酰胆碱继续增加。
氧化震颤素在30秒内产生震颤。在注射后5分钟内达到最大值，然后迅速下降。注射后5分钟脑乙酰胆碱浓度显著增加，并持续增加直至30分钟后。
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本文引用的文献
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