Gillespie J M, Broad A
Biochem J. 1969 Mar;112(1):41-9. doi: 10.1042/bj1120041.
When the diet of sheep is supplemented by the infusion of sulphur-containing amino acids or casein into the abomasum, the newly synthesized wool shows characteristic changes in its amino acid composition, with significant increases in cystine, proline and serine and decreases in aspartic acid and phenylalanine. This modification seems to be due entirely to an alteration in the overall composition of the high-sulphur proteins and to an increase in their proportion in the fibre. These variations are not the result of a change in the composition of individual proteins, but are due to alterations in their relative proportions and to the initiation of the synthesis of ;new' proteins, many of which are extremely rich in cystine. It is suggested that the heterogeneity of the high-sulphur proteins may be due, in part, to similar changes in composition caused by natural variations in the nutrition of sheep.
当通过向绵羊皱胃中注入含硫氨基酸或酪蛋白来补充其饮食时，新合成的羊毛在氨基酸组成上呈现出特征性变化，其中胱氨酸、脯氨酸和丝氨酸显著增加，而天冬氨酸和苯丙氨酸减少。这种改变似乎完全是由于高硫蛋白质的整体组成发生了变化以及它们在纤维中的比例增加所致。这些变化不是单个蛋白质组成改变的结果，而是由于它们相对比例的改变以及“新”蛋白质合成的启动，其中许多新蛋白质富含胱氨酸。有人提出，高硫蛋白质的异质性可能部分归因于绵羊营养的自然变化所引起的类似组成变化。
