Spassova M K, Golovinsky E V
Arzneimittelforschung. 1977;27(4):758-60. doi: 10.1002/chin.197732240.
A series of bis-beta-chlorethyl-, dimethyl- and diethyltriazenopyrazoles (I-IV) were synthesized. By the method of IR spectroscopy the most probable transformation form of I was shown. The compounds were tested as antibacterial agents on a series of bacterial species. It was established that only one of them (VI) possessed a low inhibitory effect. All the rest inhibited strongly the growth of Staphylococcus aureaus 209 and E. coli 387.
合成了一系列双-β-氯乙基、二甲基和二乙基三氮烯吡唑(I-IV)。通过红外光谱法显示了I最可能的转化形式。对这些化合物在一系列细菌种类上进行了抗菌剂测试。结果表明,其中只有一种(VI)具有较低的抑制作用。其余所有化合物都强烈抑制金黄色葡萄球菌209和大肠杆菌387的生长。