Zakharieva R D, Spassova M K, Karaivanova M C, Golovinsky E V
Arzneimittelforschung. 1984;34(6):661-3. doi: 10.1002/chin.198443148.
The chemical synthesis of certain mono- and bis-dialkyltriazenopyrazoles is described. In antitumor studies it was found that none of the compounds produced increase in life span (ILS) of L 1210 bearing mice or inhibition of adenocarcinoma 755 growth above the criteria established. The introduction of a second triazenogroup increases the toxicity of the compounds tested.
描述了某些单-和双-二烷基三氮烯基吡唑的化学合成。在抗肿瘤研究中发现，没有一种化合物能使荷L 1210小鼠的寿命延长（ILS），或对腺癌755的生长抑制超过既定标准。引入第二个三氮烯基团会增加所测试化合物的毒性。
