Klimov A N, Sinitsyna T A, Nagornev V A
Arkh Patol. 1975;37(11):3-16.
The article discusses the main elements of the infiltrative-combination theory of atherosclerosis, which was formulated and developed by N. N. Anichkov. The further development of the main principles of this theory at the current stage of medical science is elucidated. Analysis of the mechanisms of penetration of lipids into the vascular wall, the role of metabolism of the main substance and plasmic proteins at the initial stages of atherosclerosis shows that the new data obtained are not at variance with the fundamental principles of the N. N. Anichkov's theory but on the contrary, supplement it. Evidences on the role of immune complex of beta-lipoproteid-gamma-globulin in the development of atherosclerosis are also in complete accord with this theory.
本文讨论了由N. N. 阿尼奇科夫提出并发展的动脉粥样硬化浸润-结合理论的主要内容。阐述了该理论主要原则在当前医学科学阶段的进一步发展。对脂质渗透到血管壁的机制、动脉粥样硬化初始阶段主要物质和血浆蛋白代谢作用的分析表明，获得的新数据与N. N. 阿尼奇科夫理论的基本原理并不矛盾，相反，是对其进行了补充。关于β-脂蛋白-γ-球蛋白免疫复合物在动脉粥样硬化发展中作用的证据也与该理论完全一致。
