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Propoxyphene overdosage: a study of cases involving analgesic preparations containing dextropropoxyphene.

作者信息

Sengupta A, Peat M A

出版信息

Arch Toxicol. 1977 Jun 18;37(2):123-33. doi: 10.1007/BF00293862.

DOI:10.1007/BF00293862
PMID:577682
Abstract

Propoxyphene and paracetamol concentrations have been determined in blood, urine, liver blood and stomach contents from 17 post mortem cases in which Distalgesic (a propoxyphene and paracetamol compound preparation) was involved. Five patients admitted to hospital with suspected Distalgesic poisoning have also been investigated. In most cases the propoxyphene concentrations, but not the paracetamol concentrations, exceeded the minimum lethal levels reported. On the basis of our results it appears that of the constituents of Distalgesic, propoxyphene has a far more immediate and dangerous effect than paracetamol.

摘要

相似文献

1
Propoxyphene overdosage: a study of cases involving analgesic preparations containing dextropropoxyphene.
Arch Toxicol. 1977 Jun 18;37(2):123-33. doi: 10.1007/BF00293862.
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Survival after an overdose of Distalgesic (dextropropoxyphene and paracetamol).服用过量达而丰(右丙氧芬和对乙酰氨基酚)后的存活情况。
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本文引用的文献

1
PROPOXYPHENE HYDROCHLORIDE POISONING. REPORT OF THE FIRST FATALITY.
JAMA. 1964 Feb 8;187:460-1.
2
Propoxyphene hydrochloride, a drug of abuse.
JAMA. 1966 Jun 20;196(12):1089-91.
3
Propoxyphene dependence.
JAMA. 1969 Oct 6;210(1):135-6.
4
The fate of radiocarbon-labeled propoxyphene in rat, dog, and human.
Toxicol Appl Pharmacol. 1971 Jul;19(3):427-44. doi: 10.1016/0041-008x(71)90002-0.
5
Determination of dextropropoxyphene in organs from fatal poisoning.
Acta Pharmacol Toxicol (Copenh). 1971;30(5):330-8. doi: 10.1111/j.1600-0773.1972.tb00664.x.
6
Pulmonary edema associated with propoxyphene intoxication.
JAMA. 1971 Jan 11;215(2):259-62.
7
Incidence of propoxyphene poisoning: a report of fatal cases.
J Forensic Sci. 1974 Jan;19(1):72-80.
8
Fatal intoxication with dextropropoxyphene.右旋丙氧芬致死性中毒。
Forensic Sci. 1974 Aug;4(1):83-5. doi: 10.1016/0300-9432(74)90081-8.
9
Determination of propoxyphene in biological materials.
J Forensic Sci. 1974 Jan;19(1):81-9.
10
Deaths involving propoxyphene. A study of 41 cases over a two-year period.
JAMA. 1973 Mar 5;223(10):1125-30. doi: 10.1001/jama.223.10.1125.