Grosspietzsh R, Klink F, von Klitzing L, Endell W, Oberheuser F
Geburtshilfe Frauenheilkd. 1977 Jun;37(6):527-31.
It was examined, whether by intraamnial applicated lecithine an approaching respiratory distress syndrome could be prevented. This possibility of therapy was tested on a fetus unviable of life. It was shown by examining the lavage-fluid of the fetal lung, as well as the organ homogenates of lung; liver and gut, that the intraamnial applicated lecithine was metabolised and resynthesised in the organism. In the lung the lecithine was present as a complete molecule.
研究了通过羊膜腔内应用卵磷脂是否可以预防即将发生的呼吸窘迫综合征。这种治疗可能性在一个无法存活的胎儿身上进行了测试。通过检查胎儿肺的灌洗液以及肺、肝和肠道的器官匀浆表明,羊膜腔内应用的卵磷脂在生物体内被代谢并重新合成。在肺中,卵磷脂以完整分子的形式存在。