Herxheimer H, Bewersdorff H
Br Med J. 1969 Apr 26;2(5651):220-2. doi: 10.1136/bmj.2.5651.220.
In 13 patients with allergic asthma disodium cromoglycate protected fully only two from an allergen-induced asthmatic attack.Inhalation of disodium cromoglycate did not improve lung function in five patients with long-standing chronic asthma.Previous clinical trials do not show convincing evidence that this drug improves bronchial asthma in a high percentage of cases, but it seems to help a small minority of patients.
在13例过敏性哮喘患者中,色甘酸钠仅使2例患者完全免受变应原诱发的哮喘发作。吸入色甘酸钠对5例长期慢性哮喘患者的肺功能没有改善。以往的临床试验没有显示出令人信服的证据表明这种药物能在很大比例的病例中改善支气管哮喘,但它似乎对少数患者有帮助。