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色甘酸钠预防诱发性哮喘。

Disodium cromoglycate in the prevention of induced asthma.

作者信息

Herxheimer H, Bewersdorff H

出版信息

Br Med J. 1969 Apr 26;2(5651):220-2. doi: 10.1136/bmj.2.5651.220.

DOI:10.1136/bmj.2.5651.220
PMID:5780429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1983104/
Abstract

In 13 patients with allergic asthma disodium cromoglycate protected fully only two from an allergen-induced asthmatic attack.Inhalation of disodium cromoglycate did not improve lung function in five patients with long-standing chronic asthma.Previous clinical trials do not show convincing evidence that this drug improves bronchial asthma in a high percentage of cases, but it seems to help a small minority of patients.

摘要

在13例过敏性哮喘患者中,色甘酸钠仅使2例患者完全免受变应原诱发的哮喘发作。吸入色甘酸钠对5例长期慢性哮喘患者的肺功能没有改善。以往的临床试验没有显示出令人信服的证据表明这种药物能在很大比例的病例中改善支气管哮喘,但它似乎对少数患者有帮助。

相似文献

1
Disodium cromoglycate in the prevention of induced asthma.色甘酸钠预防诱发性哮喘。
Br Med J. 1969 Apr 26;2(5651):220-2. doi: 10.1136/bmj.2.5651.220.
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Disodium cromoglycate and induced asthma.色甘酸钠与诱发哮喘
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[Prevention of the bronchial obstruction induced by inhalation allergy with disodium cromoglycate].
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A double-blind study of disodium cromoglycate for prophylaxis of bronchial asthma.
Am Rev Respir Dis. 1971 Sep;104(3):323-30. doi: 10.1164/arrd.1971.104.3.323.
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A comparison of the inhibitory effects of ketotifen and disodium cromoglycate on bronchial responses to house dust, with special reference to the late asthmatic response.酮替芬与色甘酸钠对支气管对屋尘反应的抑制作用比较,特别提及迟发性哮喘反应。
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Disodium cromoglycate. A new drug for prevention of bronchial asthma.
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[Disodium cromoglycate (DSCG). Respiratory function tests].
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Disodium cromoglycate use in children and adolescents with asthma: correlation between plasma concentrations and protective effects for various inhalation methods.色甘酸钠在儿童和青少年哮喘患者中的应用:不同吸入方法下血浆浓度与保护作用的相关性
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Immediate and late bronchial obstructive reactions to inhalation of house dust and protective effects of disodium cromoglycate and prednisolone.吸入屋尘后即刻及迟发性支气管阻塞反应以及色甘酸钠二钠和泼尼松龙的保护作用。
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引用本文的文献

1
Role of disodium cromoglycate ("Intal") in treatment of childhood asthma.色甘酸钠(“因他舒”)在儿童哮喘治疗中的作用。
Arch Dis Child. 1970 Feb;45(239):49-53. doi: 10.1136/adc.45.239.49.
2
Effect of disodium cromoglycate on exacerbations of asthma produced by hyperventilation.色甘酸钠对过度通气诱发的哮喘发作的影响。
Br Med J. 1971 Feb 6;1(5744):317-9. doi: 10.1136/bmj.1.5744.317.
3
[Effect of cromolyne on allergen inhalation tests in occupational asthma of bakers (author's transl)].色甘酸对面包师职业性哮喘变应原吸入试验的影响(作者译)
Pneumonologie. 1974;151(2):115-26. doi: 10.1007/BF02097158.
4
Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.色甘酸钠:其作用机制、药理学、治疗效果及应用综述
Drugs. 1974;7(3):164-282. doi: 10.2165/00003495-197407030-00002.

本文引用的文献

1
[Retention of the wet portion of aerosols in the respiratory tract in normal subjects and patients with bronchial constriction].[正常受试者和支气管收缩患者呼吸道中气溶胶湿部的滞留情况]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1961;241:225-35.
2
Clinical trial of disodium cromoglycate in treatment of asthma in children.色甘酸钠治疗儿童哮喘的临床试验。
Br Med J. 1968 May 11;2(5601):340-4. doi: 10.1136/bmj.2.5601.340.
3
Disodium cromoglycate in the treatment of bronchial asthma.
Lancet. 1968 Sep 21;2(7569):655-7. doi: 10.1016/s0140-6736(68)92506-3.
4
Disodium cromoglycate in bronchial asthma.色甘酸钠治疗支气管哮喘
Lancet. 1968 Aug 3;2(7562):282. doi: 10.1016/s0140-6736(68)92384-2.
5
Disodium chromoglycate in the treatment of allergic bronchial asthma.色甘酸钠治疗过敏性支气管哮喘
Lancet. 1968 Jul 20;2(7560):137-9. doi: 10.1016/s0140-6736(68)90420-0.
6
Inhibitory effects of disodium cromoglycate on allergen-inhalation tests.
Lancet. 1968 Jul 20;2(7560):134-7. doi: 10.1016/s0140-6736(68)90419-4.
7
A double-blind trial of disodium cromoglycate in the treatment of allergic bronchial asthma.色甘酸钠治疗过敏性支气管哮喘的双盲试验。
Lancet. 1967 Sep 9;2(7515):539-42. doi: 10.1016/s0140-6736(67)90499-0.