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羊水振荡试验与卵磷脂 - 鞘磷脂比值在产前预测呼吸窘迫综合征中的比较

Amniotic fluid shake test versus lecithin-sphingomyelin ratio in the antenatal prediction of respiratory distress syndrome.

作者信息

Szabó I M, Csaba I F, Drozgyik I A, Novák P F

出版信息

Z Geburtshilfe Perinatol. 1977 Aug;181(4):260-3.

PMID:578601
Abstract

Surfactant content of 211 amniotic fluid samples raken between 28 and 42 weeks' gestations was determined by the shake test. Parallel with this also the lecithin/sphingomyelin (L/S) ratio was measured in 99 cases. When the test was positive no respiratory distress syndrome (RDS) occurred, while 25 RDS (53.34%) developed in 46 newborns with negative test and 8 RDS (15.38%) in 52 newborns with intermediate test. RDS was observed in all cases when the L/S ratio was below 1.5. At L/S ratios between 1.5 and 2.0, RDS appeared in 50% of the negative tests and 20% of the intermediate tests. However, when the L/S ratio was over 2.0 no RDS occured even in the case of negative tests. For the clinical praxis the positive test gives an exact information; no RDS is to be expected in such cases. In the case of a negative test, however, the authors think is necessary also to determine the L/S ratio.

摘要

通过振荡试验测定了211例妊娠28至42周期间采集的羊水样本中的表面活性剂含量。同时,还对99例样本测定了卵磷脂/鞘磷脂(L/S)比值。试验呈阳性时,未发生呼吸窘迫综合征(RDS),而46例试验呈阴性的新生儿中有25例(53.34%)发生了RDS,52例试验结果为中间值的新生儿中有8例(15.38%)发生了RDS。当L/S比值低于1.5时,所有病例均观察到RDS。L/S比值在1.5至2.0之间时,50%的阴性试验和20%的中间试验出现了RDS。然而,当L/S比值超过2.0时,即使试验为阴性也未发生RDS。对于临床实践而言,阳性试验能提供确切信息;此类情况下预计不会发生RDS。然而,对于阴性试验,作者认为也有必要测定L/S比值。

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