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Relation of amniotic fluid lecithin/sphingomyelin ratio and fetal asphyxia to respiratory distress syndrome in premature infants.羊水卵磷脂/鞘磷脂比值及胎儿窒息与早产儿呼吸窘迫综合征的关系。
Can Med Assoc J. 1978 Jun 10;118(11):1384-9.
2
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[Measurement of the lecithin/sphingomyelin ratio in amniotic fluid: a simple method for the assessment of fetal lung maturity].[羊水卵磷脂/鞘磷脂比值的测定：评估胎儿肺成熟度的一种简单方法]
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Comparison of amniotic fluid disaturated phosphatidylcholine and the lecithin-sphingomyelin ratio in the prediction of fetal lung maturity.羊水双饱和磷脂酰胆碱与卵磷脂-鞘磷脂比值在预测胎儿肺成熟度中的比较。
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[Determination and clinical application of the lecithin/sphingomyelin ratio in amniotic fluid by high performance liquid chromatography].[高效液相色谱法测定羊水卵磷脂/鞘磷脂比值及其临床应用]
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引用本文的文献

1
Impact of gestational age on risk of cerebral palsy: unravelling the role of neonatal morbidity.胎龄对脑瘫风险的影响：揭示新生儿发病率的作用。
Int J Epidemiol. 2022 Jan 6;50(6):1852-1863. doi: 10.1093/ije/dyab131. Epub 2021 Jun 28.
2
Neonatal respiratory distress: potential for prevention.新生儿呼吸窘迫：预防的可能性
Can Med Assoc J. 1979 May 5;120(9):1076-80.

本文引用的文献

1
THE EFFECT OF IMMATURITY AND PRENATAL ASPHYXIA ON THE LUNGS AND PULMONARY FUNCTION OF NEWBORN LAMBS: THE EXPERIMENTAL PRODUCTION OF RESPIRATORY DISTRESS.未成熟和产前窒息对新生羔羊肺部及肺功能的影响：呼吸窘迫的实验性产生
Pediatrics. 1965 Mar;35:382-92.
2
PATHOPHYSIOLOGY OF RESPIRATORY DISTRESS IN NEWBORN LAMBS. CIRCULATORY, BIOCHEMICAL, AND PATHOLOGICAL CONSIDERATIONS.新生羔羊呼吸窘迫的病理生理学。循环、生化及病理学考量。
Am J Dis Child. 1964 Oct;108:375-93. doi: 10.1001/archpedi.1964.02090010377008.
3
Surface properties in relation to atelectasis and hyaline membrane disease.与肺不张和透明膜病相关的表面特性
AMA J Dis Child. 1959 May;97(5, Part 1):517-23. doi: 10.1001/archpedi.1959.02070010519001.
4
Diagnosis of the respiratory distress syndrome by amniocentesis.通过羊膜穿刺术诊断呼吸窘迫综合征。
Am J Obstet Gynecol. 1971 Feb 1;109(3):440-5. doi: 10.1016/0002-9378(71)90342-5.
5
Acid-base, lactate, and pyruvate characteristics of the normal obstetric patient and fetus during the intrapartum period.正常产科患者及胎儿在分娩期的酸碱、乳酸和丙酮酸特征。
Am J Obstet Gynecol. 1974 Dec 1;120(7):862-7. doi: 10.1016/0002-9378(74)90331-7.
6
Factors affecting lecithin synthesis by fetal lung cells in culture.影响培养的胎儿肺细胞卵磷脂合成的因素。
Pediatr Res. 1974 Oct;8(10):848-51. doi: 10.1203/00006450-197410000-00006.
7
Variations in the levels of cytoplasmic glucocorticoid receptors in lungs of various species at different developmental stages.
Endocrinology. 1974 Feb;94(2):450-8. doi: 10.1210/endo-94-2-450.
8
Fetal lung maturity. I. Mode of onset of premature labor. Influence of premature rupture of the membranes.胎儿肺成熟度。一、早产的发病方式。胎膜早破的影响。
Obstet Gynecol. 1977 Mar;49(3):275-9.
9
Diminished pulmonary lecithin synthesis in acidosis: experimental findings as related to the respiratory distress syndrome.酸中毒时肺卵磷脂合成减少：与呼吸窘迫综合征相关的实验发现
Pediatrics. 1976 Jan;57(1):32-40.

羊水卵磷脂/鞘磷脂比值及胎儿窒息与早产儿呼吸窘迫综合征的关系。

Relation of amniotic fluid lecithin/sphingomyelin ratio and fetal asphyxia to respiratory distress syndrome in premature infants.

作者信息

Worthington D, Smith B T

出版信息

Can Med Assoc J. 1978 Jun 10;118(11):1384-9.

PMID:657031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1818360/
Abstract

In a group of 81 prematurely delivered infants the amniotic fluid lecithin/sphingomyelin ratio was related to functional fetal lung maturity. Intrapartum fetal asphyxia occurred in 33% of the group. An association between fetal asphyxia and the development of respiratory distress syndrome (RDS) in the infant was observed. When pulmonary maturity was borderline according to the amniotic fluid assessment, intrapartum fetal asphyxia was associated with an increased risk for development of RDS in the infant.

摘要

在一组81例早产婴儿中，羊水卵磷脂/鞘磷脂比值与胎儿肺功能成熟度相关。该组中33%的婴儿发生了产时胎儿窒息。观察到胎儿窒息与婴儿呼吸窘迫综合征（RDS）的发生之间存在关联。根据羊水评估，当肺成熟度处于临界状态时，产时胎儿窒息与婴儿发生RDS的风险增加相关。