肾小球涎蛋白
Glomerular sialoprotein.
作者信息
Mohos S C, Skoza L
出版信息
Science. 1969 Jun 27;164(3887):1519-21. doi: 10.1126/science.164.3887.1519.
PMID:5786643
Abstract
The high content of sialic acid in the glomerulus is associated with the cell membrane of epithelial cells lining the basement membrane. Whereas enzyme studies indicate that sialic acid is a determinant of the nephritogenic antigen, the physicochemical properties of this nephritogenic glycoprotein suggest that sialic acid may have an important role in the filtration mechanism.
摘要
肾小球中高含量的唾液酸与衬于基底膜的上皮细胞的细胞膜相关。虽然酶学研究表明唾液酸是致肾炎抗原的一个决定因素，但这种致肾炎糖蛋白的物理化学性质表明唾液酸可能在滤过机制中起重要作用。
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