Giannitsis D J
Arzneimittelforschung. 1977;27(8):1595-7.
Alcohols have a stimulating effect on the intracellular peroxidatic reactions of intact human erythrocytes. This effect depends directly on the molecular weight of alcohol and the H2O2 concentration. The human leukocyte nuclear histones, flavin-adenine-dinucleotide (FAD) and nicotinamide-adenine-dinucleotide (NAD) inhibit the peroxidatic reactions during the metabolism of alcohols in intact human erythrocytes. The participation of erythrocyte catalase, the possible metabolic pathway and the inhibitory effect of human leukocyte nuclear histones, FAD and NAD on the intracellular metabolism of alcohols is discussed.
醇类对完整人体红细胞的细胞内过氧化反应具有刺激作用。这种作用直接取决于醇类的分子量和过氧化氢浓度。人白细胞核组蛋白、黄素腺嘌呤二核苷酸（FAD）和烟酰胺腺嘌呤二核苷酸（NAD）在完整人体红细胞醇类代谢过程中抑制过氧化反应。本文讨论了红细胞过氧化氢酶的参与情况、可能的代谢途径以及人白细胞核组蛋白、FAD和NAD对醇类细胞内代谢的抑制作用。
