帕金森病中的肾素-醛固酮系统。
Renin-aldosterone system in Parkinson's disease.
作者信息
Barbeau A, Gillo-Joffroy L, Boucher R, Nowaczynski W, Genest J
出版信息
Science. 1969 Jul 18;165(3890):291-2. doi: 10.1126/science.165.3890.291.
PMID:5787986
Abstract
Low blood pressure is frequent in the akinetic form of Parkinson's disease. A low renin activity in plasma as well as a low rate of aldosterone secretion is demonstrated in these patients. Renin activity in the plasma is further decreased by treatment with L-dihy-droxyphenylalanine, thus partially accouinting for the hypotensive episodes seen with this form of therapy.
摘要
低血压在帕金森病的运动不能型中很常见。这些患者表现出血浆肾素活性低以及醛固酮分泌率低。用L-二羟基苯丙氨酸治疗会进一步降低血浆肾素活性，从而部分解释了这种治疗方式所见的低血压发作。
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