Fröscher W
Arzneimittelforschung. 1977;27(9):1729-36.
Measurement of the serum levels of antiepileptic drugs is an important progress in managing the patients with epilepsy. The determination of serum levels has become indispensable in special indications such as assessing the compliance in taking medication and identifying the responsible agent in intoxicated patients on multiple drug therapy. The long-term prognostic value of the routine determination of anticonvulsant drugs is related to the validity of the concept "therapeutic serum level".
测定抗癫痫药物的血清水平是癫痫患者治疗中的一项重要进展。在特殊情况下,如评估服药依从性以及确定接受多种药物治疗的中毒患者的责任药物时,血清水平的测定已变得不可或缺。常规测定抗惊厥药物的长期预后价值与“治疗性血清水平”这一概念的有效性相关。