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犬气管造口术所用空气的最佳湿化。扫描电子显微镜及表面活性剂研究。

Optimum humidification of air administered to a tracheostomy in dogs. Scanning electron microscopy and surfactant studies.

作者信息

Tsuda T, Noguchi H, Takumi Y, Aochi O

出版信息

Br J Anaesth. 1977 Oct;49(10):965-77. doi: 10.1093/bja/49.10.965.

Abstract

The effect of the inhalation of dried (less than 40% water-saturation) or humidified air (100% water-saturation at 25, 30, 35 and 40 degrees C) was studied in dogs in which a tracheostomy had been performed to determine the optimal humidity. After inhalation for various periods, the dogs were killed and pieces of lung tissue were excised for analysis of surfactant. Sections of the trachea and the primary to tertiary bronchi were taken for scanning electron microscopic examination. Structural changes were observed in the trachea of dogs inhaling dried at and in the tertiary bronchi of dogs inhaling 100% water-saturated air at 35 degrees C. No changes was observed after 24 h in dogs which had inhaled 100% water-saturated air at 25 degrees C under anaesthesia or at 30 degrees C without anaesthesia. Consequently, the optimal range of humidity was determined to be 100% water-saturation between 25 and 30 degrees C.

摘要

为确定最佳湿度,对已行气管切开术的犬吸入干燥空气(水饱和度低于40%)或湿化空气(25、30、35和40摄氏度下100%水饱和度)的效果进行了研究。在吸入不同时长后,处死犬并切除肺组织块用于表面活性剂分析。取气管及一级至三级支气管切片进行扫描电子显微镜检查。在吸入干燥空气的犬的气管以及吸入35摄氏度下100%水饱和空气的犬的三级支气管中观察到结构变化。在麻醉状态下吸入25摄氏度下100%水饱和空气或在非麻醉状态下吸入30摄氏度下100%水饱和空气的犬,24小时后未观察到变化。因此,确定最佳湿度范围为25至30摄氏度之间的100%水饱和度。

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