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弥漫性毒性甲状腺肿患者脊髓中枢的反射兴奋性(关于运动障碍的发病机制)

[Reflex excitability of the spinal centers in patients with diffuse toxic goiter (concerning the pathogenesis of motor disorders)].

作者信息

Gaĭdina G A, Gol'ber L M, Kalenova N P, Lazareva S P, Prikhozhan V M

出版信息

Probl Endokrinol (Mosk). 1977 Sep-Oct;23(5):24-9.

PMID:579253
Abstract

Reflex activity of the spinal cord motor centres was studied in patients with diffuse toxic goiter and in healthy persons. Methods of recording N- and M-responses of the soleus muscle were used. It was revealed that the number of motor neurons participating in the reflex reaction was changed; the restoratory cycle of the motor neuron pool was disturbed in double stimulation; inhibition of the H-reflex during the voluntary contraction of the antagonist muscle was diminished. The occuring disturbances were connected with the functional changes both of the segmental spinal cord apparatus and of the supersegmental formations. The extent and the direction of the detected disturbances are determined by the presence or the absence of affection of the mesodiencephalic formations on the patients under study and failed to depend on the severity of the disease.

摘要

对弥漫性毒性甲状腺肿患者和健康人脊髓运动中枢的反射活动进行了研究。采用记录比目鱼肌N波和M波反应的方法。结果发现,参与反射反应的运动神经元数量发生了变化;在双重刺激下,运动神经元池的恢复周期受到干扰;拮抗肌随意收缩时H反射的抑制减弱。所出现的干扰与脊髓节段性装置和超节段性结构的功能变化均有关。所检测到的干扰的程度和方向取决于所研究患者中脑间脑结构是否受到影响,而与疾病的严重程度无关。

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