Gaĭdina G A, Bakhenko S P, Alekseeva R M
Probl Endokrinol (Mosk). 1975 Jul-Aug;21(4):18-22.
Peculiarities of the reflex and motor responses of the soleus muscle were studied in stimulation of the tibial nerve by stimuli of gradually increasing intensity, and also in double stimulation and against the background of contraction of the antagonistic muscles in children with diffuse goiter and in healthy individuals. In sick children an increase and a fall in the H-response amplitude with increase of the stimulation intensity occurred more rapidly than in healthy ones. A rapid restoration of the reflex response at the interval of 500 msec and greater was noted in studying the cycle of restoration of excitation of the motor cells of the anterior horn in sick children. Against the background of contraction of the antagonistic muscles the reciprocal inhibition of the reflex response of the muscle was weaker than in the healthy individuals. The data obtained led to a supposition that one of the causes of motor disturbances in case of an excess of the thyroid hormones in the organism could be a disturbance of the processes of the pre- and postsynaptic inhibition at the spinal level.
在弥漫性甲状腺肿患儿和健康个体中，通过逐渐增加强度的刺激来刺激胫神经，研究比目鱼肌的反射和运动反应特性，同时也研究双重刺激以及在拮抗肌收缩背景下的情况。患病儿童中，随着刺激强度增加，H反射幅度的增加和下降比健康儿童更快。在研究患病儿童前角运动细胞兴奋恢复周期时，发现在500毫秒及更长间隔时反射反应能快速恢复。在拮抗肌收缩背景下，肌肉反射反应的交互抑制比健康个体弱。所获得的数据导致一种推测，即机体甲状腺激素过量时运动障碍的原因之一可能是脊髓水平突触前和突触后抑制过程的紊乱。
