Harigaya K, Watanabe S, Watanabe Y, Kageyama K, Nakazawa K
Arch Pathol Lab Med. 1977 Dec;101(12):652-4.
Pancytopenia and disseminated intravascular coagulation (DIC) developed in a 62-year-old woman. Scattered granulomatous nodules in the bone marrow, composed of numerous eosinophilic concentric spherules with amorphous eosinophilic deposits and reticulin fibrosis between them, resulted in the destruction of the bone marrow architecture. These rare morphologic appearances in the bone marrow may have been caused by lipogranulomatosis and multiple bone marrow infarctions, which were subsequent developments to DIC. Such a process is believed to have induced a lethal secondary hypoplastic anemia.
一名62岁女性出现全血细胞减少和弥散性血管内凝血（DIC）。骨髓中散在的肉芽肿性结节由大量嗜酸性同心球组成，球内有非晶形嗜酸性沉积物，其间有网状纤维组织增生，导致骨髓结构破坏。骨髓中这些罕见的形态学表现可能是由脂肪肉芽肿病和多发性骨髓梗死引起的，它们是DIC的后续发展。据信这样的过程诱发了致命的继发性再生障碍性贫血。
