用蛇毒酶安克洛酶和马拉若岛矛头蝮蛇毒巴曲酶激活血浆因子XIII 。
The activation of plasma factor XIII with the snake venom enzymes ancrod and batroxobin marajoensis.
作者信息
Walter M, Nyman D, Krajnc V, Duckert F
出版信息
Thromb Haemost. 1977 Aug 31;38(2):438-46.
The snake venom enzymes Ancrod and Batroxobin marajoensis are able to activate human plasma factor XIII as shown by the formation of the gamma-dimers. The concentration of gamma-dimers increases with the concentration of the activating enzymes. Factor XIII activated by Ancrod or Batroxobin marajoensis is, however, unable to catalyse the incorporation of the amine dansyl-cadaverine into casein. The partially activated factor XIII is therefore not demonstrable by means of the artificial test system. This factor XIII loses little activity and remains activable by thrombin.
蛇毒酶安克洛酶和马拉若岛矛头蝮蛇毒巴曲酶能够激活人血浆因子 XIII，γ-二聚体的形成即表明了这一点。γ-二聚体的浓度随激活酶浓度的增加而升高。然而，由安克洛酶或马拉若岛矛头蝮蛇毒巴曲酶激活的因子 XIII 无法催化胺基丹磺酰尸胺掺入酪蛋白。因此，通过人工测试系统无法证实部分激活的因子 XIII。这种因子 XIII 活性损失很小，且仍可被凝血酶激活。
Zotero 插件