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对与哺乳动物滑膜和耳软骨中胶原纤维紧密相关的35SO4标记物质进行电子显微镜放射自显影。

Electron microscopic autoradiography of 35SO4-labelled material closely associated with collagen fibrils in mammalian synovium and ear cartilage.

作者信息

Myers D B

出版信息

Histochem J. 1976 Mar;8(2):191-9. doi: 10.1007/BF01007168.

DOI:10.1007/BF01007168
PMID:57957
Abstract

Electron microscopic autoradiography of connective tissue obtained from mice and rabbits previously injected with 35SO4 indicated that sulphated proteoglycans are localized on collagen fibrils. Ruthenium Red-positive transverse belts surrounding fibrils near the a-bands were heavily labelled, but fine lateral filaments of Ruthenium Red-positive material were not. These filaments, which interconnect collagen fibrils in a variety of connective tissues may represent linear aggregations of hyaluronic acid, glycoproteins and non-sulphated or long-lived sulphated proteoglycans.

摘要

对先前注射过35SO4的小鼠和兔子的结缔组织进行电子显微镜放射自显影显示，硫酸化蛋白聚糖定位于胶原纤维上。围绕α带附近纤维的钌红阳性横向带被大量标记，但钌红阳性物质的细侧丝没有被标记。这些在各种结缔组织中连接胶原纤维的细丝可能代表透明质酸、糖蛋白和非硫酸化或长寿命硫酸化蛋白聚糖的线性聚集体。

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1
Electron microscopic autoradiography of 35SO4-labelled material closely associated with collagen fibrils in mammalian synovium and ear cartilage.对与哺乳动物滑膜和耳软骨中胶原纤维紧密相关的35SO4标记物质进行电子显微镜放射自显影。
Histochem J. 1976 Mar;8(2):191-9. doi: 10.1007/BF01007168.
2
Ruthenium red-positive filaments interconnecting collagen fibrils.钌红阳性细丝连接胶原纤维。
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3
Acid mucopolysaccharides closely associated with collagen fibrils in normal human synovium.酸性粘多糖与正常人滑膜中的胶原纤维紧密相关。
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An immunoelectron microscope study of the organization of proteoglycan monomer, link protein, and collagen in the matrix of articular cartilage.关节软骨基质中蛋白聚糖单体、连接蛋白和胶原蛋白组织的免疫电子显微镜研究。
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引用本文的文献

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本文引用的文献

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ON THE SITE OF SULFATION IN THE CHONDROCYTE.关于软骨细胞中硫酸化的位点
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High-resolution autoradiography. I. Methods.高分辨率放射自显影术。I. 方法。
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The relationship of hyaluronate and collagen in the bovine vitreous body.牛玻璃体中透明质酸与胶原蛋白的关系。
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Electron microscopic observations on pulmonary connective tissue stained by Ruthenium Red.用钌红染色的肺结缔组织的电子显微镜观察
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Proteoglycan-fibrillar collagen interactions.蛋白聚糖-纤维状胶原蛋白相互作用
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Ultrastructure of transport pathways in stressed synovium of the knee in anaesthetized rabbits.麻醉兔膝关节应激滑膜中转运途径的超微结构
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7
Microfibrillar meshwork of the synovial lining and associated broad banded collagen: a clue to identity.滑膜衬里的微纤维网状结构及相关宽带状胶原：身份识别的线索。
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Collagen metabolism in the liver. An annotated and supplemented report of a workshop at the National Institutes of Health on February 28 and March 1, 1977.肝脏中的胶原蛋白代谢。1977年2月28日和3月1日在美国国立卫生研究院举办的一次研讨会的注释及补充报告。
Am J Dig Dis. 1978 Jul;23(7):641-59.
J Anat. 1967 Jan;101(Pt 1):99-112.
4
[Problems of electron microscopic radioautography].[电子显微镜放射自显影术的问题]
Naturwissenschaften. 1966 Jun;53(11):268-71. doi: 10.1007/BF00621640.
5
Hyaluronic acid in cartilage and proteoglycan aggregation.软骨中的透明质酸与蛋白聚糖聚集
Biochem J. 1974 Jun;139(3):565-81. doi: 10.1042/bj1390565.
6
Dermatan sulfate-protein: isolation from and interaction with collagen.
Arch Biochem Biophys. 1968 Dec;128(3):567-78. doi: 10.1016/0003-9861(68)90064-7.
7
The interaction of collagen and acid mucopolysaccharides. A model for connective tissue.胶原蛋白与酸性粘多糖的相互作用。一种结缔组织模型。
Biochem J. 1965 Sep;96(3):710-6. doi: 10.1042/bj0960710.
8
Preservation of intercellular substances by the cationic dye alcian blue in preparative procedures for electron microscopy.在电子显微镜制备过程中，用阳离子染料阿尔辛蓝保存细胞间物质。
J Ultrastruct Res. 1970 Jun;31(5-6):424-8. doi: 10.1016/s0022-5320(70)90159-0.
9
Acid mucopolysaccharides closely associated with collagen fibrils in normal human synovium.酸性粘多糖与正常人滑膜中的胶原纤维紧密相关。
J Ultrastruct Res. 1969 Aug;28(3):203-13. doi: 10.1016/s0022-5320(69)90080-x.
10
Electron microscopic demonstration of proteoglycans in guinea pig epiphyseal cartilage.豚鼠骨骺软骨中蛋白聚糖的电子显微镜显示
J Ultrastruct Res. 1973 Dec;45(5):407-27. doi: 10.1016/s0022-5320(73)80070-x.