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[中非共和国洛巴耶地区比阿卡俾格米人中虫媒病毒病的血清流行病学调查]

[Sero-epidemiological survey of arbovirus diseases in the Bi-Aka pygmies of Lobaye, Central African Republic].

作者信息

Sureau P, Jaeger G, Pinerd G, Palisson M J, Bedaya-N'Garo S

出版信息

Bull Soc Pathol Exot Filiales. 1977 Mar-Apr;70(2):131-7.

PMID:579613
Abstract

Sero-epidemiological survey for Arboviruses among Bi-Aka Pigmies of the Lobaye, Central African Empire. A sero-epidemiological survey has been conducted, in 1975-1976, among 349 nomadic Pygmies of the Lobaye area in the Central African Empire, to investigate the prevalence of arbovirus infections. The percentages of individuals with detectable antibodies were 9,5 % for Chikungunya, 13,5 % for Semliki Forest, 5,2 % for Sindbis; 11,7 % for Bunyamwera; 2,3 % for West Nile, 6,3 % for Uganda S, and 8,9 % for Yellow Fever. These results are similar to those found in 1964 by CHIPPAUX in a comparable group of Pigmies of the same area and confirm that the prevalence of arbovirus infections is lower in the nomadic pygmies of the same area and confirm that the prevalence of arbovirus infections is lower in the nomadic Pygmies than in the sedentary Pygmies as well as in the settled bantus of the Lobaye valley villages. Yellow fever specific antibodies detected in this non vaccinated population indicate that latent infections occur in human beings living in the depth of the tropical forest, from the natural sylvatic focus of yellow fever, which remains active as recently proven in the Central African Empire by virus isolations obtained from wild caught mosquitoes.

摘要

中非帝国洛巴耶地区俾格米族人群虫媒病毒血清流行病学调查。1975 - 1976年,在中非帝国洛巴耶地区对349名游牧俾格米人进行了血清流行病学调查,以研究虫媒病毒感染的流行情况。检测到抗体的个体百分比分别为:基孔肯雅热9.5%,塞姆利基森林病毒13.5%,辛德毕斯病毒5.2%,布尼亚姆韦拉病毒11.7%,西尼罗河病毒2.3%,乌干达S病毒6.3%,黄热病8.9%。这些结果与1964年奇波在同一地区一组类似的俾格米人群中发现的结果相似,并证实同一地区游牧俾格米人虫媒病毒感染的流行率低于洛巴耶河谷村庄的定居班图人以及定居俾格米人。在这个未接种疫苗的人群中检测到黄热病特异性抗体,表明生活在热带森林深处的人群中存在潜伏感染,感染源来自黄热病的自然丛林疫源地,最近在中非帝国通过从野外捕获的蚊子中分离出病毒已证实该疫源地仍然活跃。

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