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自身免疫性甲状腺疾病中的Gm表型

Gm phenotypes in autoimmune thyroid disease.

作者信息

Farid N R, Newton R M, Noel E P, Marshall W H

出版信息

J Immunogenet. 1977 Dec;4(6):429-32. doi: 10.1111/j.1744-313x.1977.tb00927.x.

Abstract

The Gm phenotype Gm f,b or Gm f,n,b was found in all forty patients with Graves' disease studied, contrasted with thirty-five out of forty controls and twenty out of thirty-one patients with thyroiditis. The difference between the two groups with autoimmune thyroid disease was significant. These results suggest that thyroid stimulating antibodies may be allotypically restricted.

摘要

在所研究的全部40例格雷夫斯病患者中均发现了Gm表型Gm f,b或Gm f,n,b,与之形成对比的是,40名对照者中有35人以及31例甲状腺炎患者中有20人具有该表型。两组自身免疫性甲状腺疾病患者之间的差异具有显著性。这些结果表明,促甲状腺抗体可能受到同种异型限制。

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