Rapoport S I
J Gen Physiol. 1969 Aug;54(2):178-87. doi: 10.1085/jgp.54.2.178.
Volume changes of the transverse tubular system (T system) of frog sartorius in different solutions can be explained by a model which assumes fixed negative charges in the T system lumen, an open T system mouth, and a Donnan equilibrium between the T system and external solution. The T system volume is regulated by the osmotic pressure difference between the lumen and external solution, as well as by constraining forces whose nature is as yet unclear. The decreased swelling tendency produced by hypotonic solutions and increased tendency produced by some hypertonic solutions are ascribed to changes in the pressure constraint from the sarcoplasm. Fixed charge concentration was estimated tentatively from swelling and resistivity data to be between 0.1 and 0.4 M.
青蛙缝匠肌横管系统(T系统)在不同溶液中的体积变化可以用一个模型来解释,该模型假设T系统管腔内存在固定负电荷、T系统口开放,以及T系统与外部溶液之间存在唐南平衡。T系统的体积由管腔与外部溶液之间的渗透压差异以及性质尚不清楚的约束力调节。低渗溶液产生的肿胀趋势降低以及一些高渗溶液产生的肿胀趋势增加,归因于肌浆压力约束的变化。根据肿胀和电阻率数据初步估计固定电荷浓度在0.1至0.4M之间。