Freygang W H, Rapoport S I, Peachey L D
J Gen Physiol. 1967 Nov;50(10):2437-58. doi: 10.1085/jgp.50.10.2437.
Some of the linear electrical properties of frog sartorius muscle have been investigated in Ringer's fluid and in a Ringer fluid made hypertonic by the addition of sucrose or NaCl. Electrical constants were determined from measurements of the phase angle of the admittance of a fiber for an applied alternating current, from measurements of the voltage induced by an inward pulse of current, and from measurements of the conduction velocity of the action potential and the time constant of its foot. The dilation of the transverse tubular system induced by the sucrose hypertonic Ringer fluid was correlated with the change in the electrical constants. From this it is concluded that a two time constant equivalent circuit for the membrane, as proposed by Falk and Fatt, is in good agreement with our results. Both the area of the membrane of the transverse tubular system, and the capacity (c(e)) attributed to it, increased in the sucrose hypertonic Ringer fluid. The resistance r(e), which is in series with c(e), did not fall when the transverse tubular system was dilated and probably is not located in that system.
已在林格氏液以及添加蔗糖或氯化钠而变为高渗的林格氏液中研究了青蛙缝匠肌的一些线性电特性。通过测量施加交流电时纤维导纳的相角、测量内向电流脉冲所感应的电压以及测量动作电位的传导速度及其波底的时间常数来确定电常数。蔗糖高渗林格氏液所引起的横管系统扩张与电常数的变化相关。由此得出结论，如福尔克和法特所提出的，膜的双时间常数等效电路与我们的结果非常吻合。在蔗糖高渗林格氏液中，横管系统膜的面积及其电容（c(e)）均增加。与c(e)串联的电阻r(e)在横管系统扩张时并未下降，且可能并不位于该系统中。
