• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[用数字计算机测定药代动力学常数的迭代程序(作者译)]

[Iteration program for determining pharmacokinetic constants with a digital computer (author's transl)].

作者信息

Lücker P W

出版信息

Arzneimittelforschung. 1977;27(12):2371-2.

PMID:580053
Abstract

An iteration program is reported by which it will be possible to determine the constants k1 and y0 by the graphical constants tmax and k2. The program is designed for the desk-calculator HP 97. It makes a relatively exact determination of k1 and of y0 possible. By using these constants in the function of Bateman, the latter may be better defined than it would be possible by k1 determined from graphs. Furthermore application of this program saves drawing blood samples within the period of t0--tmax.

摘要

本文报道了一种迭代程序,通过该程序可以根据图形常数tmax和k2来确定常数k1和y0。该程序是为惠普97台式计算器设计的。它使得相对精确地确定k1和y0成为可能。通过在贝特曼函数中使用这些常数,该函数可以比通过从图表中确定的k1得到更好的定义。此外,应用该程序可在t0 - tmax时间段内节省采集血样的操作。

相似文献

1
[Iteration program for determining pharmacokinetic constants with a digital computer (author's transl)].[用数字计算机测定药代动力学常数的迭代程序(作者译)]
Arzneimittelforschung. 1977;27(12):2371-2.
2
[A multiple iteration program for determining global pharmacokinetic constants on a digital computer (author's transl)].[一种用于在数字计算机上确定整体药代动力学常数的多重迭代程序(作者译)]
Arzneimittelforschung. 1978;28(3):471-2.
3
Use of a programmable calculator to determine steady-state levels of drugs eliminated by parallel first-order and Michaelis-Menten kinetics.使用可编程计算器来确定通过平行一级动力学和米氏动力学消除的药物的稳态水平。
Am J Hosp Pharm. 1978 Sep;35(9):1075-7.
4
Integrated calculator programs for pharmacokinetic calculations.
Am J Hosp Pharm. 1982 May;39(5):825-8.
5
[Estimation of pharmacokinetic constants in irregular repeated drug administration (author's transl)].
Arzneimittelforschung. 1978;28(10):1766-70.
6
Determination of the number of exponential functions in pharmacokinetic models on the basis of concentration-time data by MUCOM1.
Methods Find Exp Clin Pharmacol. 1985 Dec;7(12):653-9.
7
A calculator program for estimating model-independent pharmacokinetic parameters.
Boll Chim Farm. 1984 Nov;123(11):530-8.
8
Studies on absorption and elimination of drugs. Part VI: Fitting of a double exponential curve to the observed drug concentration after single extravascular administration.
Int J Clin Pharmacol Biopharm. 1975 Dec;12(4):437-45.
9
An APL computer program for estimating rate constants of drug absorption.一个用于估算药物吸收速率常数的APL计算机程序。
Arzneimittelforschung. 1983;33(6):902-4.
10
Pharmacokinetic calculator program for generation of initial parameter estimates from a three-compartment infusion model.
J Pharmacol Methods. 1985 Aug;14(1):13-24. doi: 10.1016/0160-5402(85)90039-7.