Richter E, Zambelis N, Wick G, Ludwig H
Laryngol Rhinol Otol (Stuttg). 1978 Jan;57(1):42-5.
We developed a new method for demonstration and enumeration of antigen-binding cells, the principle and application of this method is demonstrated using peripheral blood lymphoid cells from Hashimoto patients, non-Hashimoto, non Graves' disease goiter patients and in patients without thyroid disease. A significantly higher number of thyroglobulin-binding cells was observed in the peripheral blood of Hashimoto patients as compared to members of the two other groups. The results of the FICA-tests were compared to conventional serological data of the individual patients.
我们开发了一种用于抗原结合细胞的展示和计数的新方法，使用来自桥本氏病患者、非桥本氏病非格雷夫斯病甲状腺肿患者以及无甲状腺疾病患者的外周血淋巴细胞来证明该方法的原理和应用。与其他两组的成员相比，在桥本氏病患者的外周血中观察到甲状腺球蛋白结合细胞的数量明显更多。将荧光免疫细胞分析（FICA）测试的结果与各个患者的传统血清学数据进行了比较。
