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对从牛链球菌中分离出的粘肽结构的化学研究。

Chemical studies on the structure of mucopeptide isolated from Streptococcus bovis.

作者信息

Kane J, Lackland H, Karakawa W W, Krause R M

出版信息

J Bacteriol. 1969 Jul;99(1):175-9. doi: 10.1128/jb.99.1.175-179.1969.

Abstract

Mucopeptides isolated from Streptococcus bovis cell walls were found to be composed of alanine, glutamic acid, lysine, and threonine in a mole ratio of 3:1:1:1. A dipeptide, N(epsilon)-lysylthreonine, was isolated from S. bovis mucopeptide by ion-exchange chromatography. This finding suggests that threonine is associated with the bridge which cross-links adjacent tetrapeptides by connecting the epsilon-amino group of lysine of one tetrapeptide to the carboxyl group of d-alanine of another to form the mucopeptide matrix.

摘要

从牛链球菌细胞壁分离出的粘肽被发现由丙氨酸、谷氨酸、赖氨酸和苏氨酸组成,摩尔比为3:1:1:1。通过离子交换色谱法从牛链球菌粘肽中分离出一种二肽,N(ε)-赖氨酰苏氨酸。这一发现表明,苏氨酸与通过将一个四肽的赖氨酸的ε-氨基连接到另一个四肽的d-丙氨酸的羧基上,从而交联相邻四肽的桥有关,以形成粘肽基质。

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本文引用的文献

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J Exp Med. 1966 Aug 1;124(2):155-71. doi: 10.1084/jem.124.2.155.

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