G 群链球菌特异性碳水化合物的免疫化学研究
IMMUNOCHEMICAL STUDIES ON THE SPECIFIC CARBOHYDRATE OF GROUP G STREPTOCOCCI.
作者信息
CURTIS S N, KRAUSE R M
出版信息
J Exp Med. 1964 Jan 1;119(6):997-1003. doi: 10.1084/jem.119.6.997.
Abstract
Group G hemolytic streptococcal cell walls which have been treated with trypsin are composed of a group-specific polysaccharide moiety and a mucopeptide matrix. The mucopeptide contains N-acetylglucosamine, N-acetylmuramic acid, alanine, glutamic acid, lysine, and glycine, a composition similar to that of other groups of streptococci. The Group G carbohydrate is composed of rhamnose, N-acetylgalactosamine, and galactose. Serological studies suggest that the monosaccharide of L-rhamnose is a major component of the determinant of antigenic specificity.
摘要
经胰蛋白酶处理的G群溶血性链球菌细胞壁由群特异性多糖部分和粘肽基质组成。粘肽含有N-乙酰葡糖胺、N-乙酰胞壁酸、丙氨酸、谷氨酸、赖氨酸和甘氨酸，其组成与其他组链球菌相似。G群碳水化合物由鼠李糖、N-乙酰半乳糖胺和半乳糖组成。血清学研究表明，L-鼠李糖的单糖是抗原特异性决定簇的主要成分。
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