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出血性卒中中的血液凝固与纤维蛋白溶解

Blood coagulation and fibrinolysis in haemorrhagic stroke.

作者信息

Dube R K, Rao P V, Saha P K, Katiyar B C, Dube B

出版信息

Thromb Haemost. 1978 Feb 28;39(1):84-8.

PMID:580508
Abstract

Studies of 11 patients with haemorrhagic stroke revealed no significant change in kaolin cephalin clotting time, prothrombin time, thrombin time, PF 3 availability, platelet count and factor V and VIII during the first week. Plasma fibrinogen was significantly increased while factors VII + X were decreased (borderline significance). Prolongation of plasma recalcification time and decrease in heparin tolerance reached borderline significance. There was moderate, but significant, increase in serum antithrombin activity and plasma (euglobulin fraction) fibrinolytic activity.

摘要

对11例出血性中风患者的研究显示,在第一周内,高岭土部分凝血活酶时间、凝血酶原时间、凝血酶时间、PF3活性、血小板计数以及因子V和VIII均无显著变化。血浆纤维蛋白原显著增加,而因子VII + X减少(临界显著)。血浆复钙时间延长和肝素耐受性降低达到临界显著。血清抗凝血酶活性和血浆(优球蛋白部分)纤溶活性有中度但显著的增加。

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