Sarkar K, Uhthoff H K
Arch Pathol Lab Med. 1978 May;102(5):266-9.
To determine the site of mineralization in calcifying tendinitis, we studied the ultrastructure of tendon fragments that were obtained during surgical interventions on ten patients with that condition. We found that calcification was occurring extracellularly and essentially in areas where the tendon had undergone cartilaginous transformation. Calcific crystals were present in matrix-vesicle-like structures that were seen either singly among collagen fibers or in aggregates. When they were in aggregates, the calcifying vesicles tended to fuse with each other. Thus, the process of mineralization in calcifying tendinitis resembled those calcifying conditions that have already been described in man and animals, both normal and pathological, in which the apatite crystals are initially localized in matrix vesicles.
为确定钙化性肌腱炎的矿化部位，我们研究了10例钙化性肌腱炎患者手术干预时获取的肌腱碎片的超微结构。我们发现钙化发生在细胞外，主要发生在肌腱已发生软骨转化的区域。钙盐结晶存在于基质小泡样结构中，这些结构可见于胶原纤维之间单个存在或聚集成团。当它们聚集成团时，钙化小泡往往相互融合。因此，钙化性肌腱炎的矿化过程类似于人类和动物中已描述的正常和病理钙化情况，其中磷灰石晶体最初定位于基质小泡中。
