Witzleben C L, Pinto M
Arch Pathol Lab Med. 1978 Jun;102(6):306-11.
Two cases of a distinctive infantile myocardiopathy were studied by light and electron microscopy. They represent the 15th and 16th reported examples of this condition, and include the first associated with morphologically classical endocardial fibroelastosis. The condition is characterized by the presence of clusters of foamy or granular cells scattered throughout the myocardium. Ultrastructural studies indicate (1) that lipid storage is not a feature of the condition, and (2) that the abnormal fibers are characterized by a reduced number of fibrils and an increased number of mitochondria. It is proposed that the lesion should be called "foamy myocardial transformation of infancy," and it is speculated that the condition is an acquired metabolic disorder, perhaps occurring in patients abnormally predisposed to such an acquisition.
通过光学显微镜和电子显微镜对两例特殊的婴儿心肌病进行了研究。它们是该病症报道的第15和16例，其中首例伴有形态学上典型的心内膜弹力纤维增生症。该病症的特征是心肌中散在分布着泡沫状或颗粒状细胞簇。超微结构研究表明：（1）脂质储存并非该病症的特征；（2）异常纤维的特点是肌原纤维数量减少而线粒体数量增加。建议将该病变称为“婴儿期泡沫状心肌转化”，据推测该病症是一种后天性代谢紊乱，可能发生在对此类病变具有异常易感性的患者中。
