Cozzutto C, Soave F
Virchows Arch A Pathol Anat Histol. 1979 Dec;385(1):103-8. doi: 10.1007/BF00433545.
A case of an unusual type of granulomatous lymphadenitis, initially suspected of being a malignant lymphoma, is reported. Histologically, this lesion shows a striking xanthomatous appearance, due to collections of foamy histiocytes interspersed with chronic inflammatory cells, and resulting in a storage-like aspect. Evidence indicates that this process merely represents the reabsorption and healing phases of an acute suppurative lymphadenitis, with histopathologic features comparable to those of xanthogranulomatous pyelonephritis. The term xanthogranulomatous lymphadenitis is suggested for this previously inadequately described lesion, and the likely non-specific degenerative character of the xanthomatous response is stressed.
本文报告一例罕见类型的肉芽肿性淋巴结炎，最初怀疑为恶性淋巴瘤。组织学上，该病变呈现出显著的黄色瘤样外观，这是由于泡沫状组织细胞聚集并夹杂着慢性炎症细胞，从而导致类似储存的外观。有证据表明，这个过程仅仅代表急性化脓性淋巴结炎的吸收和愈合阶段，其组织病理学特征与黄色肉芽肿性肾盂肾炎相似。对于这个之前描述不足的病变，建议使用“黄色肉芽肿性淋巴结炎”这一术语，并强调黄色瘤样反应可能具有的非特异性退行性特征。
