Kraus-Mackiw E, Georgs K, Immich H, Müller-Ruchholtz W
Klin Monbl Augenheilkd. 1975 Dec;167(6):844-6.
When giving details of the frequency of Sympathetic Ophthalmia a clear distinction must be made between this disorder and the Phacogenic Ophthalmia also affecting the second eye. The latter is found with lens damage, whereas genuine Sympathetic Ophthalmia in relation to enucleation, eye damage and eye opening surgery at Heidelberg University between 1937 and 1973 is less than 1%, a figure markedly below figures quoted in the earlier literature. In two out of three patients with recent genuine Sympathetic Ophthalmia we found an augmented stimulation index in the LTT with retina antigen, not choroid antigen, as compared to control groups. This can be regarded as due to an individually augmented immunologic reactivity towards eye specific tissue antigens.
在阐述交感性眼炎的发病频率细节时,必须明确区分这种疾病与同样会累及另一只眼睛的晶状体源性眼炎。晶状体源性眼炎是由晶状体损伤引起的,而1937年至1973年间在海德堡大学进行的与眼球摘除、眼外伤和开眼手术相关的真正交感性眼炎发病率低于1%,这一数字明显低于早期文献中引用的数据。在最近发生真正交感性眼炎的三分之二患者中,与对照组相比,我们发现淋巴细胞转化试验(LTT)中针对视网膜抗原而非脉络膜抗原的刺激指数升高。这可被视为是由于个体对眼特异性组织抗原的免疫反应性增强所致。