Butler M J
Thromb Haemost. 1978 Apr 30;39(2):488-95.
Thrombelastography has been performed on recalcified whole blood from 50 patients before, during and after elective abdominal surgery. The characteristic changes of the thrombelastographic indices r, k and mA are described. During operation r and k shortened, but no change in mA was observed. This response was in part associated with an increase in factor VIII activity. Following operation, while r time was somewhat shortened, much more marked changes in k and mA were evident. Increasing fibrinogen concentration was the dominant factor in determining the post-operative changes in the thrombelastograph.
对50例择期腹部手术患者术前、术中和术后重新钙化的全血进行了血栓弹力图检查。描述了血栓弹力图指标r、k和mA的特征性变化。手术期间，r和k缩短，但mA未见变化。这种反应部分与因子VIII活性增加有关。术后，虽然r时间有所缩短，但k和mA的变化更为明显。纤维蛋白原浓度增加是决定术后血栓弹力图变化的主要因素。
