Narang S, Kaw J L, Zaidi S H
Acta Pharmacol Toxicol (Copenh). 1978 May;42(5):337-42. doi: 10.1111/j.1600-0773.1978.tb02213.x.
The effect of parenteral administration of iron (dextran) on the number of asbestos fibers in the lungs, formation of asbestos bodies and the development of interstitial fibrosis was studied in guinea pigs exposed intratracheally to anthophyllite dust. The treatment did not accelerate, either qualitatively or quantitatively, the formation of asbestos bodies or retard the development of interstitial fibrosis. The number of naked asbestos fibers was also similar in anthophyllite-inoculated animals to those similarly inoculated, but having had, additionally, a previous saturation with iron.
在气管内暴露于直闪石粉尘的豚鼠中，研究了肠胃外给予铁（右旋糖酐铁）对肺中石棉纤维数量、石棉小体形成以及间质性纤维化发展的影响。该治疗在定性或定量方面均未加速石棉小体的形成，也未延缓间质性纤维化的发展。在接种直闪石的动物中，裸石棉纤维的数量与同样接种但先前已用铁饱和的动物相似。
