Suppr超能文献

老年患者的甲状腺功能亢进症

[Hyperthyroidism in older patients].

作者信息

Brun R, Jenny M, Junod J P

出版信息

Schweiz Med Wochenschr. 1978 Sep 30;108(39):1504-10.

PMID:581312
Abstract

This study comprises 81 thyrotoxic patients with onset after the age of 60. In elderly persons, toxic multinodular goiter is the most common cause (68%) of hyperthyroidism, followed by solitary thyroid nodules (16%) and Graves' disease (16%). Cardiovascular disorders (cardiac failure, arrythmias etc.) constitute the first and often the only symptom in 62% of the cases. The other forms of appearance are both various and deceptive: depression, slight fever, asthenia or nausea. Separate analysis of the three forms of hyperthyroidism did not reveal clinical, biological or therapeutic differences between them, except an inferior rate of captation for the toxic nodules. Isolated measurement of T3 or T4 is often insufficient to confirm the diagnosis because either of these hormones may appear at a normal rate. In three cases only the free thyroxin index was pathological on first determination. The authors have established that the autonomous nodules are larger and more active after, rather than before, 60 years of age, and have attempted to define their morphological identity. The results of the treatment are analyzed and preference is expressed for radioactive iodine in every form of hyperthyroidism.

摘要

本研究包含81例60岁以后发病的甲状腺毒症患者。在老年人中,毒性多结节性甲状腺肿是甲状腺功能亢进最常见的病因(68%),其次是孤立性甲状腺结节(16%)和格雷夫斯病(16%)。心血管疾病(心力衰竭、心律失常等)在62%的病例中是首要且常常是唯一的症状。其他表现形式多样且具有欺骗性:抑郁、低热、乏力或恶心。对三种甲状腺功能亢进形式进行单独分析未发现它们之间在临床、生物学或治疗方面存在差异,只是毒性结节的摄取率较低。仅检测T3或T4往往不足以确诊,因为这两种激素中的任何一种都可能以正常水平出现。仅在3例患者首次检测时游离甲状腺素指数异常。作者已证实自主性结节在60岁之后比之前更大且更活跃,并试图明确其形态特征。对治疗结果进行了分析,并表明放射性碘对各种形式的甲状腺功能亢进均为首选。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验