Ma K W, Golbus S M, Kaufman R, Staley N, Londer H, Brown D C
Arch Pathol Lab Med. 1978 Oct;102(10):527-9.
A patient who had been treated for Hodgkin's disease was infected with herpes zoster. Shortly thereafter, glomerulonephritis mediated by anti-glomerular basement membrane (anti-GBM) antibody occurred. The diagnosis was confirmed by the presence of circulating anti-GBM antibody, immunofluorescence, and elution. Results of immunofluorescence of a lymph node disclosed deposits of IgG on the vascular and stromal connective tissue, in a pattern similar to that seen when heterologous anti-GBM antibody reacted with the node. Because of the known nephritogenic potential of solid lymphoid tissues, this finding suggests a possible relationship between his tumor and his glomerular disease. The role of zoster infection remains undefined.
一名曾接受霍奇金病治疗的患者感染了带状疱疹。此后不久，发生了由抗肾小球基底膜（anti-GBM）抗体介导的肾小球肾炎。通过循环抗GBM抗体、免疫荧光和洗脱试验确诊。淋巴结免疫荧光结果显示IgG沉积于血管和间质结缔组织，其模式与异源抗GBM抗体与淋巴结反应时所见相似。由于已知实体淋巴组织具有致肾炎潜力，这一发现提示其肿瘤与肾小球疾病之间可能存在关联。带状疱疹感染的作用仍不明确。
