人血小板、病毒与抗体之间的相互作用。IV. 风疹后血小板减少性紫癜与风疹抗原 - 抗体相互作用引起的血小板聚集
Interaction between human blood platelets, viruses and antibodies. IV. Post-Rubella thrombocytopenic purpura and platelet aggregation by Rubella antigen-antibody interaction.
作者信息
Myllylä G, Vaheri A, Vesikari T, Penttinen K
出版信息
Clin Exp Immunol. 1969 Mar;4(3):323-32.
Abstract
A new method of measuring antibodies by observing sedimentation patterns of platelets has been compared with the complement fixation and haemagglutination inhibition techniques in ten cases of and seven cases of post- thrombocytopenic purpura. The method is based on the aggregation of platelets by the joint action of antibody and small size antigens. The platelet aggregation method gave exceptionally high titres in cases of post- thrombocytopenic purpura. Other serologic methods did not give these high titres. The hypothesis that small size virus antigen and antibody against it are both needed to induce thrombocytopenia during the recovery period is discussed. Large amounts of both may result in clinical symptoms.
摘要
一种通过观察血小板沉降模式来测量抗体的新方法，已在10例[具体疾病未提及]和7例血小板减少性紫癜患者中与补体结合和血凝抑制技术进行了比较。该方法基于抗体和小尺寸抗原的联合作用使血小板聚集。在血小板减少性紫癜病例中，血小板聚集法给出了异常高的滴度。其他血清学方法未得出这些高滴度。文中讨论了在恢复期诱导血小板减少需要小尺寸病毒抗原及其抗体两者的假设。两者含量过高可能会导致临床症状。
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本文引用的文献
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