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传染性单核细胞增多症及其他疾病中嗜异性凝集试验与保罗-邦内尔试验的比较。

A comparison of the Monospot with the Paul-Bunnell test in infectious mononucleosis and other diseases.

作者信息

Seitanidis B

出版信息

J Clin Pathol. 1969 May;22(3):321-3. doi: 10.1136/jcp.22.3.321.

Abstract

The Monospot is a spot test designed for the diagnosis of infectious mononucleosis and its efficacy has been compared with that of the standard Paul-Bunnell test. Three out of 210 (1.4%) sera from normal persons and persons suffering from diseases other than infectious mononucleosis gave ;false' positive results when compared with the Paul-Bunnell test. Using 38 sera from patients with strong clinical and haematological evidence of infectious mononucleosis no false negative results were found with the Monospot test. The sera of 37 patients gave positive results with the Paul-Bunnell test: the one negative result was positive using serum taken a few days later.

摘要

嗜异性凝集试验是一种用于诊断传染性单核细胞增多症的斑点试验,其效果已与标准的保罗-邦内尔试验进行了比较。在210份来自正常人和患有传染性单核细胞增多症以外疾病的人的血清中,有3份(1.4%)与保罗-邦内尔试验相比产生了“假”阳性结果。使用38份有传染性单核细胞增多症强烈临床和血液学证据的患者血清,嗜异性凝集试验未发现假阴性结果。37名患者的血清在保罗-邦内尔试验中呈阳性:唯一的阴性结果在几天后采集的血清检测时呈阳性。

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