Krous H F
Arch Pathol Lab Med. 1979 Feb;103(2):76-8.
Neonatal nonbacterial thrombotic endocarditis (NBTE), a rare disorder yet to be diagnosed antemortem, is described in two infants. The first infant was postmature and suffered from polycythemia and meconium aspiration. The meconium-stained placenta manifested evidence of ischemia and disseminated intravascular coagulation (DIC). The second patient was delivered near term by cesarean section, and hyaline membrane disease developed. The pathogenesis of NBTE may relate to perinatal hypoxia with transient tricuspid insufficiency, polycythemia, and DIC.
新生儿非细菌性血栓性心内膜炎（NBTE）是一种罕见疾病，生前难以诊断，本文描述了两例婴儿病例。首例婴儿为过期产儿，患有红细胞增多症和胎粪吸入综合征。胎粪污染的胎盘有缺血及弥散性血管内凝血（DIC）表现。第二例患者为剖宫产近足月分娩，发生了透明膜病。NBTE的发病机制可能与围产期缺氧伴短暂三尖瓣关闭不全、红细胞增多症及DIC有关。
