Pedespan L, Amram D, Sarlangue J, Mansir T, Fayon M, Demarquez J L
Hôpital Pellegrin-enfants, place Amélie-Raba-Léon, 33076 Bordeaux, France.
Arch Pediatr. 2001 Aug;8(8):824-7. doi: 10.1016/s0929-693x(01)00541-3.
Nonbacterial thrombotic endocarditis is not widely known in neonates.
We report three new cases which illustrate some specific aspects of this pathology. Respiratory distress with severe pulmonary hypertension, systemic hypotension and disseminated intravascular coagulopathy in a full-term newborn were characteristic findings.
An early echocardiography should lead to accurate diagnosis. Hypoxemia and genetic factors could be determining factors in its pathogenesis.