Pedespan L, Amram D, Sarlangue J, Mansir T, Fayon M, Demarquez J L
Hôpital Pellegrin-enfants, place Amélie-Raba-Léon, 33076 Bordeaux, France.
Arch Pediatr. 2001 Aug;8(8):824-7. doi: 10.1016/s0929-693x(01)00541-3.
Nonbacterial thrombotic endocarditis is not widely known in neonates.
We report three new cases which illustrate some specific aspects of this pathology. Respiratory distress with severe pulmonary hypertension, systemic hypotension and disseminated intravascular coagulopathy in a full-term newborn were characteristic findings.
An early echocardiography should lead to accurate diagnosis. Hypoxemia and genetic factors could be determining factors in its pathogenesis.
非细菌性血栓性心内膜炎在新生儿中并不广为人知。
我们报告三例新病例，这些病例说明了这种病理状况的一些特定方面。一名足月儿出现呼吸窘迫伴严重肺动脉高压、全身性低血压和弥散性血管内凝血，这些是典型表现。
早期超声心动图检查应能得出准确诊断。低氧血症和遗传因素可能是其发病机制中的决定性因素。
