Shuangshoti S, Paisuntornsook P, Netsky M G
Arch Pathol Lab Med. 1979 Mar;103(3):112-5.
Melanosis of the choroid plexus, ependyma, subependymal neuroglia of the fourth ventricle, and dentate and trigeminal motor nuclei was found in a 50-year-old man who died with cor pulmonale, hypertensive cardiovascular disease, and intracerebral hemorrhage. This case is the first known example of melanosis not associated with neurocutaneous melanosis to involve multiple structures of the brain. Nonenzymatic conversion of lipofuscin into melanin is suggested as the mechanism of the melanosis. Cilia of the choroidal epithelium and ependyma were identified in this case, despite a long delay in postmortem examination. These observations on choroidal epithelium confirm previous reports that the choroid plexus of man is ciliated, as in other mammals and lower vertebrates.
在一名死于肺心病、高血压性心血管疾病和脑出血的50岁男性中，发现脉络丛、室管膜、第四脑室室管膜下神经胶质以及齿状核和三叉神经运动核有黑色素沉着。该病例是已知首例与神经皮肤黑色素沉着无关的累及脑多个结构的黑色素沉着病例。脂褐素非酶促转化为黑色素被认为是黑色素沉着的机制。尽管尸检延迟了很长时间，但在该病例中仍鉴定出脉络膜上皮和室管膜的纤毛。对脉络膜上皮的这些观察结果证实了先前的报道，即人类的脉络丛像其他哺乳动物和低等脊椎动物一样有纤毛。
