Mayer W, Komarek A
Arzneimittelforschung. 1978;28(4):680-1.
The concentration of guanidine was determined in blood serum and urine of healthy humans following oral administration of guanidine hydrochloride. The biological half life is 12 h, the renal clearance is 40--50 ml. An improved method for the determination of guanidine in body fluids is described.
在健康人体口服盐酸胍后,测定其血清和尿液中胍的浓度。生物半衰期为12小时,肾清除率为40 - 50毫升。本文描述了一种测定体液中胍的改进方法。