从佐林格-埃利森肿瘤组织中分离出的两种胃泌素的氨基酸组成。
Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue.
作者信息
Gregory R A, Tracy H J, Agarwal K L, Grossman M I
出版信息
Gut. 1969 Aug;10(8):603-8. doi: 10.1136/gut.10.8.603.
Abstract
Two peptides which are potent stimulants of gastric acid secretion are isolated from Zollinger-Ellison tumour tissue. They have aminoacid constitutions identical with those of human gastrin types I and II as isolated from human antral mucosa, and they are present in similar proportions. Their electrophoretic and chromatographic behaviour corresponds to that of human gastrins. Evidence is presented in respect of the one isolated in greater amount that its aminoacid sequence is probably identical with that of human gastrin type I.
摘要
从佐林格-埃利森肿瘤组织中分离出两种强力胃酸分泌刺激肽。它们的氨基酸组成与从人胃窦黏膜分离出的人胃泌素I型和II型相同，且比例相似。它们的电泳和色谱行为与人类胃泌素一致。对于含量较多的那种分离肽，有证据表明其氨基酸序列可能与人胃泌素I型相同。
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