• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

膜极化对蛙缝匠肌终板电流时间进程的影响。

The effect of membrane polarization on the time course of the end-plate current in frog sartorius muscle.

作者信息

Kordas M

出版信息

J Physiol. 1969 Oct;204(2):493-502. doi: 10.1113/jphysiol.1969.sp008926.

DOI:10.1113/jphysiol.1969.sp008926
PMID:5824649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1351566/
Abstract
  1. Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique.2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0.6 msec to about 1.6 msec.3. It is suggested that the stability of receptor-mediator complex is affected by the membrane potential.
摘要

  1. 采用电压钳技术，在不同膜电位下对终板电流进行细胞内记录。

  2. 当膜电位在约+40mV至-120mV之间变化时，终板电流的半衰期从约0.6毫秒增加到约1.6毫秒。

  3. 提示受体-介质复合物的稳定性受膜电位影响。

相似文献

1
The effect of membrane polarization on the time course of the end-plate current in frog sartorius muscle.膜极化对蛙缝匠肌终板电流时间进程的影响。
J Physiol. 1969 Oct;204(2):493-502. doi: 10.1113/jphysiol.1969.sp008926.
2
The effect of voltage on the time course of end-plate currents.电压对终板电流时间进程的影响。
J Physiol. 1972 May;223(1):151-71. doi: 10.1113/jphysiol.1972.sp009839.
3
An attempt at an analysis of the factors determining the time course of the end-plate current. II. Temperature.对决定终板电流时间进程的因素的分析尝试。II. 温度。
J Physiol. 1972 Jul;224(2):333-48. doi: 10.1113/jphysiol.1972.sp009898.
4
Miniature end-plate currents in voltage-clamped muscle fibre.电压钳制肌纤维中的微小终板电流。
Nature. 1968 Apr 27;218(5139):363-5. doi: 10.1038/218363b0.
5
A quantitative description of end-plate currents.终板电流的定量描述。
J Physiol. 1972 May;223(1):173-97. doi: 10.1113/jphysiol.1972.sp009840.
6
Miniature end-plate currents and potentials generated by quanta of acetylcholine in glycerol-treated toad sartorius fibres.甘油处理的蟾蜍缝匠肌纤维中乙酰胆碱量子产生的微小终板电流和电位。
J Physiol. 1972 Oct;226(1):79-94. doi: 10.1113/jphysiol.1972.sp009974.
7
Potassium exchange and afterpotentials in frog sartorius muscles treated with glycerol.甘油处理的青蛙缝匠肌中的钾离子交换和后电位
J Gen Physiol. 1970 Dec;56(6):692-715. doi: 10.1085/jgp.56.6.692.
8
The amplitude and the time course of the end-plate current at various pH levels in the frog sartorius muscle.青蛙缝匠肌在不同pH水平下终板电流的幅度和时程。
J Physiol. 1975 Jul;249(2):183-95. doi: 10.1113/jphysiol.1975.sp011010.
9
Mechanism of blockade of neuromuscular transmission by pentobarbital.戊巴比妥阻断神经肌肉传递的机制。
J Pharmacol Exp Ther. 1975 Jan;192(1):95-104.
10
Diphasic end-plate current recorded on the glycerol treated muscle fiber.
Nihon Seirigaku Zasshi. 1970 Aug;32(8):538-9.

引用本文的文献

1
Fourth gaddum memorial lecture, school of pharmacy, university of london, january 1973.第四届加德姆纪念讲座，伦敦大学药学院，1973年1月
Br J Pharmacol. 1973 Jul;48(3):475-95. doi: 10.1111/j.1476-5381.1973.tb08355.x.
2
Voltage clamp study of fast excitatory synaptic currents in bullfrog sympathetic ganglion cells.牛蛙交感神经节细胞快速兴奋性突触电流的电压钳研究。
J Gen Physiol. 1980 Jan;75(1):39-60. doi: 10.1085/jgp.75.1.39.
3
Fast decay of fish synaptic currents.
Experientia. 1983 Feb 15;39(2):230-1. doi: 10.1007/BF01958916.
4
The voltage and temperature dependence of the end-plate current in frog skeletal muscle.青蛙骨骼肌终板电流的电压和温度依赖性
Pflugers Arch. 1984 Aug;401(4):408-13. doi: 10.1007/BF00584344.
5
Voltage clamp analysis of the effect of cationic substitution on the conductance of end-plate channels.阳离子替代对终板通道电导影响的电压钳分析
Pflugers Arch. 1982 Jul;394(1):38-47. doi: 10.1007/BF01108306.
6
Inhibition of acetylcholine responses by intracellular calcium in Lymnaea stagnalis neurones.椎实螺神经元内钙对乙酰胆碱反应的抑制作用。
J Physiol. 1982 Feb;323:1-19. doi: 10.1113/jphysiol.1982.sp014058.
7
A study of desensitization of acetylcholine receptors using nerve-released transmitter in the frog.一项关于利用青蛙神经释放的递质对乙酰胆碱受体进行脱敏作用的研究。
J Physiol. 1981 Jul;316:225-50. doi: 10.1113/jphysiol.1981.sp013784.
8
An attempt to distinguish between the actions of neuromuscular blocking drugs on the acetylcholine receptor and on its associated ionic channel.区分神经肌肉阻断药物对乙酰胆碱受体及其相关离子通道作用的尝试。
Proc Natl Acad Sci U S A. 1980 Aug;77(8):5003-7. doi: 10.1073/pnas.77.8.5003.
9
The effect of papaine on the time course of the end-plate current.
Pflugers Arch. 1980 Jul;386(1):67-70. doi: 10.1007/BF00584189.
10
Miniature end-plate currents and potentials generated by quanta of acetylcholine in glycerol-treated toad sartorius fibres.甘油处理的蟾蜍缝匠肌纤维中乙酰胆碱量子产生的微小终板电流和电位。
J Physiol. 1972 Oct;226(1):79-94. doi: 10.1113/jphysiol.1972.sp009974.

本文引用的文献

1
An analysis of the end-plate potential recorded with an intracellular electrode.用细胞内电极记录的终板电位分析。
J Physiol. 1951 Nov 28;115(3):320-70. doi: 10.1113/jphysiol.1951.sp004675.
2
Effects of calcium on the conductance change of the end-plate membrane during the action of transmitter.钙对递质作用期间终板膜电导变化的影响。
J Physiol. 1963 Jun;167(1):141-55. doi: 10.1113/jphysiol.1963.sp007137.
3
Some properties of conductance changes at the end-plate membrane during the action of acetylcholine.乙酰胆碱作用期间终板膜电导变化的一些特性。
J Physiol. 1963 Jun;167(1):128-40. doi: 10.1113/jphysiol.1963.sp007136.
4
On the permeability of end-plate membrane during the action of transmitter.递质作用期间终板膜的通透性
J Physiol. 1960 Nov;154(1):52-67. doi: 10.1113/jphysiol.1960.sp006564.
5
Active phase of frog's end-plate potential.青蛙终板电位的活动期
J Neurophysiol. 1959 Jul;22(4):395-411. doi: 10.1152/jn.1959.22.4.395.
6
Properties of the procaine end-plate potential.普鲁卡因终板电位的特性。
Jpn J Physiol. 1957 Sep 30;7(3):199-212. doi: 10.2170/jjphysiol.7.199.
7
The membrane change produced by the neuromuscular transmitter.神经肌肉递质产生的膜变化。
J Physiol. 1954 Sep 28;125(3):546-65. doi: 10.1113/jphysiol.1954.sp005180.
8
Frog skeletal muscle fibers: changes in electrical properties after disruption of transverse tubular system.青蛙骨骼肌纤维：横管系统破坏后电特性的变化
Science. 1967 Dec 29;158(3809):1700-1. doi: 10.1126/science.158.3809.1700.
9
Action potentials without contraction in frog skeletal muscle fibers with disrupted transverse tubules.横小管遭到破坏的青蛙骨骼肌纤维中出现无收缩的动作电位。
Science. 1967 Dec 29;158(3809):1702-3. doi: 10.1126/science.158.3809.1702.
10
Analysis of sodium and potassium conductances in the procaine end-plate potential.普鲁卡因终板电位中钠电导和钾电导的分析。
J Physiol. 1966 Apr;183(3):592-606. doi: 10.1113/jphysiol.1966.sp007886.