Campbell E J, Minty K B
Lancet. 1976 Jun 5;1(7971):1199-203. doi: 10.1016/s0140-6736(76)92156-5.
In a number of circumstances pulmonary function is so disturbed that inspired oxygen concentrations of about 60% are needed to combat arterial hypoxaemia. Rational therapy requires that the inspired concentration be controlled and not vary with the patient's breathing. An exploration of the interaction between gas flow, ventilation, breathing pattern, and mask volume shows that a mask of 300 ml volume supplied with a flow of 30 1/min (15 1 O2, 15 1 air) can meet the need.
在许多情况下,肺功能受到严重干扰,需要吸入约60%的氧气浓度来对抗动脉低氧血症。合理的治疗要求控制吸入浓度,且不随患者呼吸而变化。对气流、通气、呼吸模式和面罩容积之间相互作用的研究表明,容积为300 ml、流速为30 l/min(15 l氧气、15 l空气)的面罩能够满足需求。