1,2 - 二苯乙胺作为潜在的非刺激性食欲抑制剂。
1,2-Diphenylethylamines as potential non-stimulant anorectics.
作者信息
Ghosh P, Bolt A G, Mrongovius R I
出版信息
Arzneimittelforschung. 1978;28(9):1561-4.
PMID:582555
Abstract
A series of 1,2-diphenylethylamines has been synthesized in which the phenyl rings were substituted with Cl, OCH3 or CF3 at various positions and in various combinations. Four N-ethylpiperazino and N-ethylmorpholino compounds were also prepared. When tested in rats, some of the compounds were found to be potent anorectics and none of them stimulated motor activity.
摘要
已经合成了一系列1,2 - 二苯乙胺，其中苯环在不同位置和以不同组合被氯、甲氧基或三氟甲基取代。还制备了四种N - 乙基哌嗪基和N - 乙基吗啉基化合物。在大鼠身上进行测试时，发现其中一些化合物是强效食欲抑制剂，并且它们都不会刺激运动活性。
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