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内分泌性眼病的诊断与治疗(作者译)

[The diagnosis and therapy of endocrine ophthalmopathy (author's transl)].

作者信息

Horst W, Glanzmann C

出版信息

Klin Monbl Augenheilkd. 1979 Jun;174(6):969-77.

PMID:582614
Abstract

Radio-iodide diagnosis of the thyroid is a simple method of high security in the diagnosis of endocrine ophthalmopathy. This procedure is valuable especially, in cases where neither clinically, nor in the sero-hormonal diagnosis a disturbance of the thyroid can be found. In many cases an accelerated intrathyroidal turnover of radio-iodide can identify an unclear ophthalmopathy as an endocrine ophthalmopathy. The therapy of choice for hyperthyreoidism with endocrine ophthalmopathy is 131-iodide resection. This statement has been proven by our own experiences in more than 1000 cases in the past 15 years and by the results indicated in early literature about the course of ophthalmopathy after surgical or medical treatment. For the therapy of a malign, or imminent malign endocrine ophthalmopathy, we use percutane irradiation of the orbit with sparing of the lens in a dose of 200 rad 5 times a week. In practically all cases, this therapy eliminates the consequence of visual disturbances and avoids surgical decompression.

摘要

放射性碘对甲状腺的诊断是诊断内分泌性眼病的一种安全性高的简单方法。该方法尤其在临床上和血清激素诊断均未发现甲状腺功能紊乱的情况下具有重要价值。在许多病例中,甲状腺内放射性碘的周转加快可将不明原因的眼病确诊为内分泌性眼病。伴有内分泌性眼病的甲状腺功能亢进症的首选治疗方法是131碘切除术。过去15年中我们自身超过1000例的经验以及早期文献中关于手术或药物治疗后眼病病程的结果均证实了这一说法。对于恶性或即将发展为恶性的内分泌性眼病的治疗,我们采用每周5次、剂量为200拉德、对晶状体进行保护的经皮眼眶照射。在几乎所有病例中,这种治疗可消除视力障碍的后果并避免手术减压。

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1
[The diagnosis and therapy of endocrine ophthalmopathy (author's transl)].内分泌性眼病的诊断与治疗(作者译)
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2
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3
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Endocrine ophthalmopathy and radioiodine therapy.内分泌性眼病与放射性碘治疗
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MMW Munch Med Wochenschr. 1977 Jul 15;119(28):945-8.
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