Schiantarelli P, Murmann W, Lupi G
Arzneimittelforschung. 1978;28(7):1146-53.
A sulfomucopolysaccharide complex extracted from bovine pancreas displayed marked inhibitory activity against every one of a broad series of experimental inflammation models. No standard antiinflammatory drug has such all-inclusive action. The complex also exerts intense anticomplement activity in vitro. The potential antiatherosclerotic interest of this type of activity is suggested, in the light of recent hypotheses regarding the relevance of inflammatory and immune factors to the etiopathogenesis of atherosclerosis.
从牛胰腺中提取的一种硫代粘多糖复合物对一系列广泛的实验性炎症模型均显示出显著的抑制活性。没有一种标准抗炎药具有如此广泛的作用。该复合物在体外还具有强烈的抗补体活性。鉴于最近有关炎症和免疫因素与动脉粥样硬化发病机制相关性的假说，这种活性在抗动脉粥样硬化方面的潜在价值得以凸显。
